Why 308nm excimer laser therapy can treat vitiligo?

What is 308 excimer laser treatment for vitiligo?

In clinic, 308 excimer laser treatment for vitiligo is very useful and effective for vitiligo treatment. And in many countries, 308 laser treatment is a common therapy for vitiligo. 308nm excimer laser is one kind of excimer laser, meaning Xecl excimer laser. It belongs to continuous pulsed gas laser. The wavelength is during the range of UVB, and the pulse width is usually 10-30 ns.

Nowadays, the causes and pathogenesis of vitiligo are still not clear yet. There are many hypothesis to explain various clinical manifestation of different vitiligo patients.

Why 308nm excimer laser therapy can treat vitiligo?

Its therapy mechanism may be related to T lymphocyte apoptosis. Bian2chi and other people have researched by using immunohistochemical method that 308nm excimer laser can clean up the infiltrative T lymphocyte at lesion positions. Novak and others have researched that 308nm excimer laser can promote the activated T lymphocyte at vitiligo lesion positions apoptosis. The treatment effect is quite obvious, even more obvious than NB-UVB’s ability to cause apoptosis.

After 308 laser irradiation, it can lead to Tlymphocyte apoptosis, thus making the vitiligo lesions disappear not only from naked eye levels, but also making the structures recover to be normal on micro level. Vitiligo is characteristic by selective melanophore, it may relate to patients’ autoimmune response. Narrow band ultraviolet( NB-UVB) may have immunomodulatory effects to make human cells and body fluid generate immunity, which can help to stabilize depigmentation progress. Besides, NB-UVB has been widely identified as similar as PUVA(psoralen photochemical therapy), which can stimulate remained melanophore to gather around peripheral hair follicle outer root sheath. Melanophore can go on mitosis, the generation and movement of melanin, always be induced by various cytokines and inflammatory mediator, including interleukin, tumor necrosis factor α, leukotriene C4. Recent researches indicate that after UVB irradiation, various cytokines and inflammatory mediator will increase, which indicates that this is on mechanism of UVB inducing the restore of melanin.

If you have any vitiligo questions , you can leave your messages ,  i will replay you as soon as possible.

Beijing Zhongke Vitiligo Hospital

Vitiligo Treatment Options in 2023

Vitiligo is a condition where the human body inhibits the pigment producing process of the skin’s pigment cells. This process causes the formation of white patches on the skin on all areas of the body. Surprisingly, the same patches can appear on the tissues inside the mouth and nose as well as in the inner layer of the eyeball. Hair can turn white as well.

The Light Energy + Conduction Therapy directly worked on the Shenque , Quchi and Neiguan acupoints on patient’s body. Those acupoints communicate with the twelve meridians of human body directly. The Light Energy + Conduction Therapy led the medicine permeate into the diseased area, thus increase the effect of Chinese traditional herbal medicine.

Through the effect of light energy, the therapy will transport the nutrition that necessary for melanophore (the cell that can synthesis the melanin) through the microcirculation, and recover the regular function of melanophore.

The therapy will recover the damaged melanophore, recall the activity of tyrosinase in serum, and reduce the period of treatments.

Light Energy + Conduction Therapy can achieve the goal to dredge the meridians of human body, regulate the internal organs and immunity system, promote the blood circulation and microcirculation, promote the re-pigment of disease area.

Narrowband Light Therapy

Narrow-band ultraviolet B (nbUVB) therapy is a form of light treatment where patients are treated in a light booth two to three times a week at a dermatologist’s office or using a home unit. Light therapy – also known as phototherapy – involves regular, brief exposure to ultraviolet (UV) light. The UV rays stimulate melanocytes, the cells in the skin responsible for producing pigment. The key to light therapy is that monitored administration is important for safety and treatment success as too much light could burn the skin, while too little light could lack results. The pros? According to the UMass Vitiligo Clinic and Research Center, nbUVB is currently the most successful treatment for patients with vitiligo. The cons? Treatment comes with a significant time commitment and results can disappear if patients do not keep up with treatment.

Excimer Laser


The excimer laser is a form of light treatment that delivers a highly-focused beam of UVB using a wand-like device. Using a 308nm wavelength of light, which has proven to be effective at treating vitiligo, the laser may stimulate repigmentation in the skin. Although highly effective, it works best when treating small areas of skin. Patients will typically visit their dermatologist’s office for treatments twice a week over four to six months and about 70% of patients see positive results. Pros? It’s highly effective, quick and works well for small areas of vitiligo patches. Cons? It’s time intensive with multiple sessions required over a course of several months.

How to Cure vitiligo with Chinese Medicine

Q: I have white patches on my hands and fingers, elbows, armpits, hips, knees and one foot. I have been taking the vitamin suplementation (vit. D3, B12, Zinc, vit. C, copper and some pills for the liver) and for 2,5 years used UVB treatment. My vitiligo stopped. The patches are not spreading on my body since about 4 years. And I have a partial repigmentation on every patch. But I still have some old white patches, which I want to get rid of. I have a rather pale complexion an my vitiligo is barely seen, but it it bothers me, especially during summer. Do you sell some creams and medications, or maybe you have some advice what to do to get rid of this skin disorder forever?

A: First of all, you should know that different parts have different chances to get cured. For example, acral parts and mucosal parts (like hands, feet, lips, private parts and nipples) are more complicated than other parts, actually, they have little chance to get cured. But don't worry about others, they have much more possibilities to be cured. Nevertheless, much patience should be given because vitiligo is a chronic skin disorder.
So based on your case, the treatment process will be like this,
To avoid vitiligo spreading
To make your orignal skin color back, i mean parts except for acral parts and mucosal parts.
To avoid white patches come again

Secondly, let me tell you something about treatment here. Here in our hospital, vitiligo is treated with physical therapies mainly, Chinese herbal medicine should be taken as supplymentary. Which means that you must come for physical therapies if you really want to access to treatment here. Because some distinctive ones used here are only avaiable in our hospital around the world. With them, patients could get a good improvement.

Characteristic Treatment of Vitiligo in beijing zhongke vitiligo hospital

UM-D Multi Dimensions Treatment System holds that view: vitiligo is a kind of local skin melanocyte apoptosis disease.

Characteristic Treatment of Vitiligo in beijing zhongke vitiligo hospital

Why melanocyte apoptosis or decreases?
The cause is the local skin tissue’s immune system, nutrition environment, and metabolism environment are destroyed.
Then, why skin local melanin production environments are destroyed?
In Chinese medical opinion the cause is human heredity, life environment and habits that trigger the internal organs disorder.
Therefore, vitiligo treatment is not only treat skin, but also adjusting internal organs that is the 1+1+1 UM-D multi dimensions treatments.
Only by this way, we can really control vitiligo’s expansion, once the expansion is controlled that can be the premise of recovery.
1. Firstly, control vitiligo spreading therapy
It is the basic vitiligo treatment. The common treatments apply phototherapy and local external medication, even stimulating local skin to show color change, while the treatment difficulty is big, effectiveness is not that ideal. Many patients didn’t get the expected effectiveness, but losing their confidence of treatments.
2. Re pigmentation
According to the local skin area’s change, melanin can normal product, the skin color gradually recovery to original color.
3. Preventing relapse
From the long term curative aspect, we should take personal condition, internal organs function adjustment into consideration.
Our treatments combined traditional Chinese medicine, western treatments and medicine, and the latest large-scale medical facilities.

You can compare the current treatments, you can figure out the real cause why the vitiligo effects are not ideal and obvious.

Vitiligo Doctor - Zhao mingguo

Zhao MingGuo, who specializes in diagnosis and treatment of vitiligo for more than 30 years, has extensive experiences treating patients with vitiligo of all ages, particularly for patients whose skin condition is quite long-term and severe. He advocates that vitiligo must be treated not only totally-locally but internally-externally in order to get the improvement as soon as possible. For over decades, thousands of patients have already been pushed out of their mire. Besides, he was invited to attend  World Nobel Laureate Biomedical Summit and be interviewed by CCTV (China Central Television) , as well as local TV. He is also a member of editorial board of Chinese Medical Journal and Chinese Vitiligo magazine. Recognized as an important role of domestic normalized diagnosis and treatment of vitiligo by experts and patients, he takes prides of treating patients with vitiligo well. 

Vitiligo Video : Epidermal Grafting To Treat Vitiligo

Vitiligo Video : How to treat vitiligo 2019

Treatment for vitiligo by chinese medicine and UM-D Therapy 

The Latest Treatment for vitiligo 2019

Vitiligo is a long-term skin condition characterized by patches of the skin losing their pigment. The patches of skin affected become white and usually have sharp margins. The hair from the skin may also become white. The inside of the mouth and nose may also be involved. Typically both sides of the body are affected. Often the patches begin on areas of skin that are exposed to the sun. It is more noticeable in people with dark skin. Vitiligo may result in psychological stress and those affected may be stigmatized.
1. Mechanism
308 excimer laser therapy combined the most advanced technologies together, such as 308nm XeCl excimer light source, 154 Hz nanometer modulation, the technology of liquid light source transmission, and etc.
According to the clinical researches, the light with 308nm wavelength is the best light that could induce the apoptosis of the pathological T-cell, and effective in the therapy of vitiligo, psoriasis and many other skin diseases. In the therapy of vitiligo, the laser directly radiated on the diseased area, and led the a serious of biochemical reactions to promote the synthesis of skin pigment (the melanin), thus achieve the goal of recover the vitiligo.

II. Light Energy + Conduction Therapy
Action Mechanism
The Light Energy + Conduction Therapy directly worked on the Shenque , Quchi and Neiguan acupoints on patient’s body. Those acupoints communicate with the twelve meridians of human body directly. The Light Energy + Conduction Therapy led the medicine permeate into the diseased area, thus increase the effect of Chinese traditional herbal medicine.
Through the effect of light energy, the therapy will transport the nutrition that necessary for melanophore (the cell that can synthesis the melanin) through the microcirculation, and recover the regular function of melanophore.
The therapy will recover the damaged melanophore, recall the activity of tyrosinase in serum, and reduce the period of treatments.

Light Energy + Conduction Therapy can achieve the goal to dredge the meridians of human body, regulate the internal organs and immunity system, promote the blood circulation and microcirculation, promote the re-pigment of disease area.

Vitiligo Causes, Symptoms and Treatment

Vitiligo occurs when the cells that produce melanin die or stop functioning. Vitiligo affects people of all skin types, but it may be more noticeable in people with darker skin. The condition is not life-threatening or contagious. It can be stressful or make you feel bad about yourself.

The main sign of vitiligo is patchy loss of skin color. Usually, the discoloration first shows on sun-exposed areas, such as the hands, feet, arms, face and lips.
Vitiligo signs include:
Patchy loss of skin color
Premature whitening or graying of the hair on your scalp, eyelashes, eyebrows or beard
Loss of color in the tissues that line the inside of your mouth and nose (mucous membranes)
Loss of or change in color of the inner layer of the eyeball (retina)
Causes
The exact causes of vitiligo are unclear. A number of factors may contribute.
These include:
an autoimmune disorder, in which the immune system becomes overactive and destroys the melanocytes
a genetic oxidative stress imbalance
a stressful event
harm to the skin due to a critical sunburn or cut
exposure to some chemicals
a neural cause
heredity, as it may run in families
a virus
Vitiligo is not contagious. One person cannot catch it from another.
Many treatments are available to help restore skin color or even out skin tone. Results vary and are unpredictable. Some treatments have serious side effects. So your doctor may suggest that you first try improving the appearance of your skin by applying self-tanning products or makeup.
No drug can stop the process of vitiligo — the loss of pigment cells (melanocytes). But some drugs, used alone or with light therapy, can help restore some skin tone.
Creams that control inflammation. Applying a corticosteroid cream to affected skin may help return color, particularly if you start using it early in the disease. You may not see a change in your skin's color for several months.
Surgery
Surgery may be an option for you if light therapy doesn't work. Surgery can also be used with those therapies. The goal of the following techniques is to even out your skin tone by restoring color.

Skin grafting. In this procedure, your doctor removes very small sections of your normal, pigmented skin and attaches them to areas that have lost pigment. This procedure is sometimes used if you have small patches of vitiligo.

Main Symptoms of Vitiligo in the Children

The main sign of vitiligo is patchy loss of skin color. Usually, the discoloration first shows on sun-exposed areas, such as the hands, feet, arms, face and lips.
Vitiligo signs include:

• Patchy loss of skin color
• Premature whitening or graying of the hair on your scalp, eyelashes, eyebrows or beard
• Loss of color in the tissues that line the inside of your mouth and nose (mucous membranes)
• Loss of or change in color of the inner layer of the eyeball (retina)
• Vitiligo can start at any age, but often appears before age 20.

Depending on the type of vitiligo you have, the discolored patches may cover:
Many parts of your body. With this most common type, called generalized vitiligo, the discolored patches often progress similarly on corresponding body parts (symmetrically).

• Only one side or part of your body. This type, called segmental vitiligo, tends to occur at a younger age, progress for a year or two, then stop.
• One or only a few areas of your body. This type is called localized (focal) vitiligo.

It's difficult to predict how your disease will progress. Sometimes the patches stop forming without treatment. In most cases, pigment loss spreads and eventually involves most of your skin. Rarely, the skin gets its color back.

How to treat vitiligo on the face

When you have vitiligo on face , you may be upset or depressed about the change in your appearance. There are several things you can do to cope with the disorder:

Find a doctor who knows how to treat vitiligo. The doctor should also be a good listener and be able to provide emotional support.
Learn about the disorder and treatment choices. This can help you make decisions about your treatment.
Talk with other people who have vitiligo. A vitiligo group can help you find a support group (check your local listings). Family and friends are another source of support.
UM-D treatment is a suit of treatment newly researched by Beijing zhongke Vitiligo Hospital to specific to treat stubborn vitiligo, is a diagnosis and treatment system, it perfectly combined traditional Chinese medicine with western medicine along with some large scale medical equipment, it also use Chinese medicated bath, gas bath, water therapy, electroacupuncture, silicon light, carbon light, eximer laser, NB-UVB, patent Chinese medicines, western medicines and other treatments, it absorbed the essence of both traditional Chinese medicine and western medicine.

UM-D treatment is a suit of treatment newly researched by Beijing zhongke Vitiligo Hospital to specific to treat stubborn vitiligo, is a diagnosis and treatment system, it perfectly combined traditional Chinese medicine with western medicine along with some large scale medical equipment, it also use Chinese medicated bath, gas bath, water therapy, electroacupuncture, silicon light, carbon light, eximer laser, NB-UVB, patent Chinese medicines, western medicines and other treatments, it absorbed the essence of both traditional Chinese medicine and western medicine.
Learn about how to cure vitiligo on Genitals

Vitiligo Diet:What Can i Eat With Vitiligo

If you or someone you know suffers from vitiligo, then you understand how traumatic, difficult to treat, and embarrassing this skin condition can be. It’s characterized by white irregular patches on different parts of the body. The most commonly affected areas include hands, face, neck, armpits, and legs. This disorder occurs when melanin-producing cells, melanocytes, are destroyed.

In most cases it begins with a small area that loses its pigment and then expands over time. Although there is no cure for this skin condition, it is possible to slow down or even stop the pigment loss. One essential remedy is to keep a vitiligo diet. This article will elaborate on what you need to eat and what you need to avoid.
Foods Rich in Vitamin B-12
Regular eating of foods with high amounts of vitamin B-12 may help relieve the symptoms of vitiligo. This is according to a research published in 2011 in the Journal of Clinical Laboratory Analysis, which indicated that deficiency in vitamin B-12 increases homocysteine, a compound which plays a role in destroying pigment in some areas of the body. Therefore, it is highly recommended that you boost your intake of vitamin B-12 to help improve your condition. Examples of foods to take include liver, soy milk, salmon, yogurt, trout, clams, as well as haddock. You can also get the vitamin from meat, fish and some dairy products, but there are not recommended .
Foods Rich in Folic Acid
Studies have revealed that low levels of folate contribute to pigment loss. Therefore, increasing your intake of foods rich in folic acid can help manage the disease. Examples of foods to take include broccoli, spinach, asparagus, black-eyed peas, as well as breakfast cereals.
Additionally, broccoli and spinach contain phytochemicals that help lower homocysteine (a compound that destroys melanin) levels in the blood. As a result, these foods prevent cell degeneration and help protect the skin.
Also, consider adding oats to your vitiligo diet, if you’re not already taking them. Oats not only protect the skin but also improve digestion, thanks to its high amount of fiber.
Foods Rich in Zinc
Consuming foods with high amounts of zinc can also improve the condition. That is according to a study published in 2009 in the Indian Journal of Dermatology, which suggested that zinc supplementation can help cure vitiligo. Excellent sources of zinc include oysters, lobsters, crab, pork, chicken, nuts, as well as dried beans and peas.
Foods Rich in Vitamin C, Iron, Beta-carotene and Anti-oxidants

Foods high in vitamin C, iron, beta-carotene, and anti-oxidants are very good for you. The examples include spinach, carrots, tomatoes, kiwi, strawberries, cantaloupes, grapefruits, and potatoes among others. Make sure that you have a lot of tomatoes because tomatoes contain lycopene, a powerful anti-oxidant and excellent source of vitamin C. However, be careful not to overcook any of these food items, as it destroys their nutrients and power.
learn about vitiligo cause :vitiligo cause and solution

How to Cure Vitiligo ?Who Can have Vitiligo Easily

Vitiligo is a disease in which the pigment cells of the skin, melanocytes, are destroyed in certain areas.Approximately 20% of vitiligo patients have a family member with the same condition. However, only 5% to 7% of children will get vitiligo even if a parent has it.

Who Can have Vitiligo Easily
Vitiligo seems to be somewhat more common in people with certain autoimmune diseases, including:
hyperthyroidism (an overactive thyroid gland)
adrenocortical insufficiency (the adrenal gland does not produce enough of the hormone called corticosteroid)
alopecia areata (patches of baldness)
pernicious anemia (a low level of red blood cells caused by the failure of the body to absorb vitamin B12).
Scientists do not know the reason for the association between vitiligo and these autoimmune diseases. However, most people with vitiligo have no other autoimmune disease.
How to cure vitiligo
Many patients think vitiligo is not cure , it is not Very accurate, some vitiligo conditional can be cured .
The theory that Chinese medicine treat vitiligo: through promoting blood circulation to remove blood stasis, improving microcirculation, increasing blood and oxygen supply at vitiligo affected part, promoting body to make tyrosine,inhibiting melanin damaged, preventing vitiligo continue spread, by increasing chi and energizing to reach the goal that melanophore growing and activate rest broken melanophore; through tonifying kidney plus modulate, relieves depression and tranquilization, reach whole the balance of yin and yang, immunity overall coordination, to precaution vitiligo relapse after recovery.

The theory that modern medicine treat vitiligo: first intervene to prevent diseased melanophore to duplicate and spread, enable to control vitiligo enlarge in short term. Through recover the melanophore with genetic chain dis-function, remove the reason cause melanophore metabolic disorders and die, make pathological melanophore recover its normal function. Through improving the microcirculation and increasing effectively blood perfusion around illness part, ensure the new melanophore autonomously move to vitiligo part evenly, make body can regeneration melanophore from itself, solve melanophore apoptosis from root,as result of stop vitiligo, reconversion skin, remission illness on long term.

Symptoms of Segmental, Focal Vitiligo

Vitiligo is a continual and long-term skin problem that produces patches of white depigmentation that develop and enlarge in certain sections of the skin.

Segmental or focal: White patches tend to be smaller and appear in one or a few areas. When vitiligo appears in a focal or segmental pattern, it tends to stay in one area one side of the body. Many times it continues for a year or so, then stops. It also progresses slower than generalized vitiligo.
Non-segmental or generalized: Widespread white patches appear symmetrically on both sides of the body. This is the most common pattern and can affect pigment cells anywhere on the body. If often starts and stops many times over the course of a person’s lifetime. There’s no way to determine when, if, or how fast patches will develop.
One study showed that 75 percent of people with vitiligo have loss of pigment on the hands and face. Other common areas are in body folds, like the skin under your arms and around your groin.

Vitiligo commonly affects body folds (such as armpits), places that have been injured in the past, and areas exposed to sun, around moles, or around body openings. It can also affect eyelids and hair.

What Are Symptoms of Segmental Vitiligo

Most people who have vitiligo, if it is not related to another disease, report feeling physically healthy.
The condition does not cause pain or irritation, but it often affects people's self-image, which can be emotionally distressing.
The primary symptom of vitiligo is patches of skin that lighten or turn white. It commonly affects sun-exposed areas first, including your face, lips, arms, hands, and feet.

Other vitiligo signs include:
Lightening of skin around your armpits and belly button (navel)
Premature (before the age 35) whitening or graying of your hair, including the hair on top of your head, eyelashes, or facial hair (such as eyebrows and beard)
Loss of color in your mucus membranes, including your lips or the tissues inside your mouth, nose, rectum, or genitals
Loss of color in your eye's retina (which may look like a change in color)
Vitiligo may also affect the pigment cells that are part of your inner-ear system, which can cause partial or total hearing loss.
Hearing loss isn't common with vitiligo, but tell your doctor about any hearing loss or changes, especially if you are under 40 years old.
Segmental vitiligo is also known as unilateral vitiligo. Symptoms include:
Patches that appear on one side and one limb of the body, such as one side of your face, or on one leg or arm
Loss of hair color, affecting the hair on your head, eyelashes, eyebrows, or other facial hair

Discolorations at an early age that progress for about a year and then stop
Learn about Symptoms and Causes of Vitiligo