Saturday, July 30, 2016

Vitamin B12 And Vitiligo

Vitamin B12 is a water-soluble vitamin used by every cell of the body for metabolism. It is also known as cobalamin and it is the vitamin with the most complex structure.

Due to overwhelming demand, VitiligoTreatment has added to its list of products our new Vitamin B12 and Folic acid supplement tablets. Taken once a day, you have 2 months supply in each bottle.
It is well documented and the Vitiligo community are well aware that the presence of these elements is vital to the prevention of Vitiligo.
If you do already have Vitiligo and it is spreading quickly, these vitamins do slow down the spread and in many cases stop the further spread of the Vitiligo condition.
Note that this product is great in maintaining a good functioning immune system.
Vitamin B12 is essential for a healthy immune system, and without it your metabolism cannot run smoothly.
This essentially leads to the further spread of Vitiligo. Approximately 15% of people don’t get enough vitamin B12 from their diet.
Vitamin B12 deficiency leads to a disturbance in the oxidation-antioxidant system of the skin.
When there is not enough vitamin B12, the conversion of homocysteine to methionine does not proceed. This leads to metabolic diseases arising from low levels of methionine but, just as importantly, it causes other conditions related to the buildup of homocysteine.
The breakdown of homocysteine produces reactive oxygen species which are harmful free radicals that increase the oxidative stress on the skin. These free radicals overwhelm the antioxidants found in the skin and cause the destruction of melanocytes.
By a similar mechanism, vitamin B12 deficiency may increase oxidative stress through folic acid deficiency.
The folic acid ingested in humans is needed to supply the pterine group of tetrahydrobiopterine, an important cofactor in the production of melanin. However, when this cofactor is unavailable, there is an accumulation of a group of related compounds called pteridines.
Oxidized pteridines are responsible for the distinctive yellow-green and bluish fluoresce of vitiligo skins under special lights. They also promote the release of hydrogen peroxide which breaks down the melanocytes.

In summary, vitamin B12 is useful in the treatment of vitiligo because it reduces the oxidative stress on melanocytes. By its antioxidant protection, it increases the lifespan of melanocytes. As long as some melanocytes are still active, vitamin B12 can also stimulate the repigmentation of vitiligo spots.

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