Psoralen tincture is a common treatment of vitiligo drugs, if used properly
can play a very good therapeutic effect, otherwise it may be side effects, and
even exacerbations. Here is my experience for your reference.
① master the indications: psoralen tincture is mainly used for the scalp, trunk, limbs border clear white (white), if the border is not clear white generally do not;
② reasonable usage: must be psoralen tincture (note not "drop" up) in the central white, not the whole piece of white are wiped, because the psoralen tincture will spread out, if the whole piece of white are wiped It will infiltrate the surrounding normal skin, causing two consequences: white skin around the white, so that the white spot is more clear; white range expansion (isotype reaction). If the white spot is small, then use a toothpick (with scissors to cut its tip) on the drug, wipe the white central.
③ auxiliary light: pure wiping psoralen tincture if not combined light (daylight or NB-UVB), then there is no effect, so "wiping psoraline tincture + light" is a whole.
⑴ psoralen tincture + daylight: the general white (pure white) first psoriasis tincture, after 3-5 minutes, according to daylight, usually once a day. The length of the light depends on the strength of the sun, if the sun is strong, then the first 5-10 seconds, if the white spot is not red, then gradually extend the light time until the white hair; if the sun is weak, you can From 2-3 minutes, gradually extend the light time until the white spot redness. Then stop the sun exposure, local topical hormone ointment, 2 times a day until the erythema subsided, white and restore the original white, then began to use external psoraline tincture + sun exposure, so the cycle repeated.
Note: remember to wipe the psoralen tincture in the light after a long time exposure, it is likely to cause blisters !!!!!
⑵ psoralen tincture + NB-UVB: general white (white) first apply psoralen tincture, 3-5 minutes later, irradiation NB-UVB, every other day irradiation. The first day of exposure, irradiation time extended to 10 seconds; if not red, then the first 4 days without exposure, the first 5 days of exposure to the first day of the day, , The time extended to 15 seconds, and so on, until the white blood red, then stop NB-UVB irradiation, local topical hormone ointment, 2 times a day until the erythema subsided, white and restore the original white, then began to use psoralen tincture + NB-UVB irradiation, so the cycle repeated.
If some patients are very sensitive to psoralen tincture, wiping psoralen tincture in the weak light or irradiation NB-UVB 5 seconds from the blisters, this case will use alcohol or liquor (degrees limit ) Diluted with psoralen tincture and then diluted, according to the volume of dilution, such as a bottle of psoralen tincture plus 5 bottles of liquor or alcohol, diluted 5 times after the external use, if it is easy to blister, then diluted 10 times , 20 times and so on. If you can not afford blisters do not have to dilute.
① master the indications: psoralen tincture is mainly used for the scalp, trunk, limbs border clear white (white), if the border is not clear white generally do not;
② reasonable usage: must be psoralen tincture (note not "drop" up) in the central white, not the whole piece of white are wiped, because the psoralen tincture will spread out, if the whole piece of white are wiped It will infiltrate the surrounding normal skin, causing two consequences: white skin around the white, so that the white spot is more clear; white range expansion (isotype reaction). If the white spot is small, then use a toothpick (with scissors to cut its tip) on the drug, wipe the white central.
③ auxiliary light: pure wiping psoralen tincture if not combined light (daylight or NB-UVB), then there is no effect, so "wiping psoraline tincture + light" is a whole.
⑴ psoralen tincture + daylight: the general white (pure white) first psoriasis tincture, after 3-5 minutes, according to daylight, usually once a day. The length of the light depends on the strength of the sun, if the sun is strong, then the first 5-10 seconds, if the white spot is not red, then gradually extend the light time until the white hair; if the sun is weak, you can From 2-3 minutes, gradually extend the light time until the white spot redness. Then stop the sun exposure, local topical hormone ointment, 2 times a day until the erythema subsided, white and restore the original white, then began to use external psoraline tincture + sun exposure, so the cycle repeated.
Note: remember to wipe the psoralen tincture in the light after a long time exposure, it is likely to cause blisters !!!!!
⑵ psoralen tincture + NB-UVB: general white (white) first apply psoralen tincture, 3-5 minutes later, irradiation NB-UVB, every other day irradiation. The first day of exposure, irradiation time extended to 10 seconds; if not red, then the first 4 days without exposure, the first 5 days of exposure to the first day of the day, , The time extended to 15 seconds, and so on, until the white blood red, then stop NB-UVB irradiation, local topical hormone ointment, 2 times a day until the erythema subsided, white and restore the original white, then began to use psoralen tincture + NB-UVB irradiation, so the cycle repeated.
If some patients are very sensitive to psoralen tincture, wiping psoralen tincture in the weak light or irradiation NB-UVB 5 seconds from the blisters, this case will use alcohol or liquor (degrees limit ) Diluted with psoralen tincture and then diluted, according to the volume of dilution, such as a bottle of psoralen tincture plus 5 bottles of liquor or alcohol, diluted 5 times after the external use, if it is easy to blister, then diluted 10 times , 20 times and so on. If you can not afford blisters do not have to dilute.
